The “Dark Side” of Chromatin Remodeling

The “Dark Side” of Chromatin Remodeling Repressive Effects on Transcription

octamer relative to the DNA. The movement of a histone octamer along the DNA must involve the breaking and reestablishment of histone–DNA contacts within the nucleosome, but exactly how the histone–DNA contacts are altered is not known. In theory, the ATP-driven trans-location of a chromatin remodeling complex along the The packaging of the eukaryotic genome into chromatin DNA could directly br...

The “Dark Side” of Chromatin Minireview Remodeling: Repressive Effects on Transcription

octamer relative to the DNA. The movement of a histone octamer along the DNA must involve the breaking and reestablishment of histone–DNA contacts within the nucleosome, but exactly how the histone–DNA contacts are altered is not known. In theory, the ATP-driven trans-location of a chromatin remodeling complex along the The packaging of the eukaryotic genome into chromatin DNA could directly br...

O Brave New World: The Dark Side of Cyberspace

This article focuses on some of the negative aspects of cyberspace andcyberculture. First, it offers an examination of the impact of our use ofsocial media, and Facebook in particular, on our psyches, pointing out thatusers of social media can be thought of as audiences. These audiencesand information about them can be sold to marketers and advertisers.Next, it offers a case study of a widespre...

The Biochemistry of Chromatin Remodeling.

The dark side of cosmology: dark matter and dark energy.

A simple model with only six parameters (the age of the universe, the density of atoms, the density of matter, the amplitude of the initial fluctuations, the scale dependence of this amplitude, and the epoch of first star formation) fits all of our cosmological data . Although simple, this standard model is strange. The model implies that most of the matter in our Galaxy is in the form of "dark...